A novel and convenient synthesis of 4-hydroxy-6-methyl-3-(1-(phenylimino) ethyl)-2H-pyran-2-one derivatives under ultrasound irradiation

Add time:08/14/2019    Source:sciencedirect.com

A facile, efficient and environment-friendly protocol for the synthesis of 4-hydroxy-6-methyl-3-(1-(phenylimino)ethyl)-2H-pyran-2-one derivatives has been developed by the convenient ultrasound-mediated condensation of amine with dehydroacetic acid. This method provides several advantages over current reaction methodologies including a simple work-up procedure, shorter reaction times and higher yields.

► A series of 4-hydroxy-6-methyl-3-(1-(phenylimino)ethyl)-2H-pyran-2-one derivatives have been synthesized under ultrasound irradiation. ► Ultrasonic irradiation was found to have beneficial effect on the synthesis of these Schiff bases. ► All the proposed reactions allowed the preparation of products in good yield without any further complicated refinement.

We also recommend Trading Suppliers and Manufacturers of ethyl 6-methyl-4-(3-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (cas 110448-29-8). Pls Click Website Link as below: cas 110448-29-8 suppliers

Prev:Photophysical study of 6-amino-3-methyl-4-(4-nitrophenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile and estimation of ground-state and singlet excited-state dipole moments by solvatochromic approaches
Next:Research paperRemoval of tetracycline hydrochloride from aqueous solution by three 3D uranyl-organic frameworks)