Research paperPoly(2-hydroxy-3-phenoxypropylacrylate, 4-hydroxybutyl acrylate, Dibutyl maleate (cas 105-76-0)) membrane controlled clonidine zero-order release

Add time:08/14/2019    Source:sciencedirect.com

Poly(2-hydroxy-3-phenoxypropylacrylate, 4-hydroxybutyl acrylate, dibutyl maleate) membrane was synthesized by UV curing method in our laboratory for the first time. When above-mentioned monomers were in the weight ratio of 4:4:2, the membrane not only had perfect permeation property but also had excellent plasticity, so the membrane made from monomers in the ratio of 4:4:2 was chosen as an optimized membrane. The optimized membrane provided perfect linear permeation properties in clonidine transdermal drug delivery system. The permeation rate decreased in proportion to the thickness of membrane. When the concentrations of clonidine were in the range of 0.5–7.0 mg/ml, the permeation rate was proportional to the square root of clonidine concentrations. The optimized membrane was characterized by FTIR, DSC and SEM.

We also recommend Trading Suppliers and Manufacturers of Dibutyl maleate (cas 105-76-0). Pls Click Website Link as below: cas 105-76-0 suppliers

Prev:Experimental measurements and thermodynamic modeling of the cloud point pressure for solubility of copolymers of vinyl acetate and Dibutyl maleate (cas 105-76-0) in supercritical CO2
Next:Poly(ethylene terephthalate) (PET) degradation during the Zn catalysed transesterification with Dibutyl maleate (cas 105-76-0) functionalized polyolefins)