Determination of the l-isomer in d-penicillamine by derivatization liquid chromatography
-
Add time:08/19/2019 Source:sciencedirect.com
A method for a fast quantitative determination of the l-isomer in d-penicillamine is described. l-Leucine is coupled to d,l-penicillamine and the resulting diastereomers separated by reversed phase liquid chromatography. The mild conditions for the derivatization cause no racemization. For detection the UV-absorption of the derivatives at a wavelength of 215 nm is used. A linear signal was gained in a concentration range of 0.05–10% l-isomer in d-penicillamine. One complete determination can be carried out in 1.5–2 h. A comparison of products from different manufacturers resulted in the detection of l-penicillamine in the material of only one producer.
We also recommend Trading Suppliers and Manufacturers of L-Penicillamine (cas 1113-41-3). Pls Click Website Link as below: cas 1113-41-3 suppliers
Prev:Effect of L-Penicillamine (cas 1113-41-3) hydantoin, an analogue of glutathione, on rat liver glutathione peroxidase, reductase and transferase reactions
Next:Characterisation of GEA 3175 on human platelets;: comparison with S-nitroso-N-acetyl-D,L-Penicillamine (cas 1113-41-3)) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- An anti-vitamin B6 action of L-Penicillamine (cas 1113-41-3)08/22/2019
- Research letterMutagenicity experiments on l-cysteine and d-penicillamine using V79 cells as indicators and for metabolic activation08/21/2019
- Characterisation of GEA 3175 on human platelets;: comparison with S-nitroso-N-acetyl-D,L-Penicillamine (cas 1113-41-3)08/20/2019
- Effect of L-Penicillamine (cas 1113-41-3) hydantoin, an analogue of glutathione, on rat liver glutathione peroxidase, reductase and transferase reactions08/18/2019
- Aminoacylation of rat liver transfer RNA with L-Penicillamine (cas 1113-41-3): On the specificity of the aminoacylation reaction08/17/2019
- Transport of D- and L-Penicillamine (cas 1113-41-3) by mammalian cells08/16/2019
- Enantiomeric reversed-phase high-performance liquid chromatography resolution of d-/L-Penicillamine (cas 1113-41-3) after spirocyclization with ninhydrin and by using copper(II)-l-proline complex as a chiral selector in the mobile phase08/15/2019
- Application of an unusual ninhydrin-based reaction for the indirect chiral resolution of d,L-Penicillamine (cas 1113-41-3)08/14/2019
- d-Penicillamine and l-cysteine derived thiazolidine catalysts: an efficient approach to both enantiomers of secondary alcohols08/13/2019
