Aryl 2-acetamido-2-deoxy-β-D-glucopyranosides —potential anti-inflammatory agetns
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Add time:08/14/2019 Source:sciencedirect.com
Acetochlorglucosamine was reacted with the presence of potassium t-butoxide in dimethyl-formamide with salicylaldehyde, salicyclic acid, methyl salicylate, methyl 3-methylsalicylate, salicylamide and 4-acetamidophenol to give, after de-O-acetylation, a series of aryl 2-acetamido-2-deoxy-β-d-glucopyranosides. The stability of the compounds in acid and alkali and their hydrolysis by the enzyme β-N-acetylglucosaminidase were briefly studied.
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