Synthesis and structure determination of some derivatives of the antibiotic thermorubin (cas 11006-83-0)

Add time:08/16/2019    Source:sciencedirect.com

Reactions of thermorubin (1), an antibiotic produced by Thermoactinomyces antibioticus, with conventional reagents such as CH3NH2, NaBH4, HCHO/R2NH were studied. Several derivatives were obtained whose structures were determined on the basis of chemical and spectroscopic data. Some compounds showed strong modifications of the original structure.

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