Efficient method for preparation of N-methoxy-N-methyl amides by reaction of lactones or esters with Me2AlClMeONHMe·HCl

Add time:08/15/2019    Source:sciencedirect.com

The reaction of a lactone or an ester with dimethylaluminum chloride and N, O-dimethylhydroxylamine hydrochloride provided an efficient method for preparation of N-methoxy-N-methyl amide.

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