Synthesis of 2,4,5-triarylated imidazoles via three-component domino reaction under catalyst-free conditions

Add time:07/12/2019    Source:sciencedirect.com

A one-pot synthesis of 2,4,5-triarylated imidazoles via three-component domino reaction of 2,2-dibromo-1,2-diarylethanones, ammonium acetate, and aryl aldehydes under catalyst-free conditions is developed. The scope of this reaction is studied. A possible mechanism is proposed based on experimental results.

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