Colmmobilization of L-α-glycerophosphate oxidase with catalase and its application for the synthesis of dihydroxyacetone phosphate

Add time:08/22/2019    Source:sciencedirect.com

The oxidation of L-α-glycerophosphate (1) to dihydroxyacetone phosphate (2) is carried out enzymatically under aerobic conditions by L-α-glycerophosphate oxidase coimmobilized with catalase, which serves for the decomposition of the generated hydrogen peroxide. 2 is trapped in an aldolase reaction with D/L-glyceraldehyde (3). The coimmobilized enzymes show an increased operational stability and can be reused in further transformations without loss of activity.

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