Antimicrobial activity of eumelanin (cas 12627-86-0)-based hybrids: The role of TiO2 in modulating the structure and biological performance

Add time:08/19/2019    Source:sciencedirect.com

Eco-friendly hybrid Eumelanin-TiO2 nanostructures, recently obtained through in situ methodology based on hydrothermal route, have shown a striking antimicrobial activity, after exposure to oxidative environment, even under visible light induction condition. Nevertheless, the role of each component in defining the efficacy of these biological properties is far from being clearly defined. Furthermore, the effect of oxidative step on hybrids structure has not yet addressed. This study aims at elucidating the role of the ratio between eumelanin precursor, 5,6-dihydroxyindole-2-carboxylic acid (DHICA), and TiO2, for its polymerization in defining morphology and structural organization of TiO2-melanin nanostructures.Furthermore, tests on a Gram-negative Escherichia coli DH5α strain under UV irradiation and even visible light allowed to assess the contribution of each component, as well as of the TiO2–DHICA charge transfer complex to overall biological performance. Finally, results of biocide characterization were combined with spectroscopic evidences to prove that oxidative treatment induces a marked structural modification in melanin thus enhancing overall antimicrobial efficacy.

We also recommend Trading Suppliers and Manufacturers of eumelanin (cas 12627-86-0). Pls Click Website Link as below: cas 12627-86-0 suppliers

Prev:Determination of eumelanin (cas 12627-86-0) and pheomelanin in melanomas using solid-phase extraction and high performance liquid chromatography–diode array detection (HPLC-DAD) analysis
Next:Fluorescence properties of natural eumelanin (cas 12627-86-0) biopolymer)