Synthesis, crystal structure and dynamic behavior of naphthalene-based calix[3]amide: Cyclic trimers of 2-alkylamino-6-naphthoic acid

Add time:08/19/2019    Source:sciencedirect.com

Treatment of 6-amino-2-naphthoic acid with dichlorotriphenylphosphorane afforded a new naphthalene ring-based calix[3]amide in moderate yield. The macrocyclic calix[3]amide exists in an anti-form in the crystalline state and forms a channel structure along its b axis. In CDCl3 solution it exists in equilibrium between the syn- and anti-forms in solution (100:57). The energy barrier between the anti- to syn-forms was calculated to be 17.8 ± 0.2 kcal/mol.

We also recommend Trading Suppliers and Manufacturers of 6-AMINO-2-NAPHTHOIC ACID (cas 116668-47-4). Pls Click Website Link as below: cas 116668-47-4 suppliers

Prev:Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid
Next:Chiroptical sensing of amino acids by stereodynamic imprinting into the ZnII-Complex generating a dihedral chirality)