Investigation of the factors influencing the molecular weight of porphyran (cas 11016-36-7) and its associated antifungal activity

Add time:08/24/2019    Source:sciencedirect.com

In the present study various extraction methodologies have been adopted to derive sulfated polysaccharides (SPs) called as porphyran (cas 11016-36-7) (POR) from low tide (LT) and high tide (HT) samples of Porphyra vietnamensis. Initially various taxonomical differences among LT and HT samples of P. vietnamensis were evaluated. Later on various physico-chemical and antifungal properties were determined. Our results suggested that P. vietnamensis collected during LT yields high percentage of SPs with relatively low molecular weight (MW) and high sulfate content than the HT sample. Among various extraction methodologies alkali modified POR yields low MW polysaccharide but surprisingly with high sulfate content which have shown improved physico-chemical and antifungal properties than chitosan (CS) without any toxicological affects. However, extensive research is further required to explore the molecular pathways inhibited or stimulated in this process.

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