Hematological MalignanciesHeterogeneous expression and function of IL-21R and susceptibility to IL-21−mediated apoptosis in follicular lymphoma cells
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Add time:08/21/2019 Source:sciencedirect.com
ObjectiveInterleukin (IL)-21, a member of the IL-2 family, has antitumor activity and is now being tested in non-Hodgkin's lymphoma in combination with anti-CD20 antibodies. IL-21 may either induce apoptosis or promote growth in different lymphoid malignancies. We therefore investigated the IL-21/IL-21R system in follicular lymphoma (FL) cells.
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