Lipase-catalyzed enantiomeric separation of 1-aryloxy-3-thiocyanatopropan-2-ols: an attempt to prepare optically active thiiranes

Add time:08/16/2019    Source:sciencedirect.com

Opening of the epoxide ring of several arylglycidyl ethers with thiocyanato anion followed by acetylation yielded racemic mixtures of 1-aryloxy-3-thiocyanato-propan-2-yl acetates. A lipase-catalyzed hydrolysis of the acetates resulted in the separation of the enantiomers. The unstable, optically active (S)-1-aryloxy-3-thiocyanatopropan-2-ols, were converted into the corresponding 2-aryloxymethyl thiiranes, which instantly polymerized to yield the optically active oligomers.

We also recommend Trading Suppliers and Manufacturers of 1-(2,4-dichlorophenoxy)propan-2-one (cas 17199-30-3). Pls Click Website Link as below: cas 17199-30-3 suppliers

Prev:Nonlinear price dynamics of S&P 100 stocks
Next:The hepatic transport of dibromosulphthalein (cas 17199-35-8))