Original articleNeuroadaptive changes in metabotropic glutamate mGlu2/3R expression during different phases of cocaine addiction in rats
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Add time:08/16/2019 Source:sciencedirect.com
BackgroundIn the cocaine addiction the development from transient into persistent neuroplastic changes strongly involves the glutamatergic system. In this respect, among glutamatergic receptors special attention is paid to the group II of metabotropic glutamatergic receptors (mGlu2/3R) which are involved in the transition from drug use to drug addiction including the relapse mechanisms.
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