Synthesis and antitumor activity of 2-(m-substituted-benzoyl)baccatin III analogs from taxinine
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Add time:08/16/2019 Source:sciencedirect.com
2-m-Azidobenzoyl and 2-m-chlorobenzoyl baccatin III analogs were prepared from taxinine, a major component in Japanese yew leaves. In this study, a novel acetyl migration from 13- to 4-hydroxyl group was observed. The antitumor activity of these compounds was evaluated.
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