One-pot synthesis of substituted 3-amino-2-nitrothiophenes and selenophenes

Add time:08/16/2019    Source:sciencedirect.com

In this work, we described an easy preparation of substituted 3-amino-2-nitrothiophenes and selenophenes. Substituted β-chloroacrylonitriles were reacted with sodium sulfide or sodium selenide and bromonitromethane to yield the expected compounds in a one-pot three-step procedure in good yields.

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