First unequivocal synthesis of 1 or 8-N-monosubstituted 1,4,8,12-TETRAAZACYCLOPENTADECANE (cas 15439-16-4)

Add time:08/16/2019    Source:sciencedirect.com

A novel method derived from Kaden's modification1 of the Richman and Atkins's cyclization2 using tosylated synthons allows the unequivocal synthesis of 1 and 8-monofunctionalized 1,4,8,12-tetraazacyclo-pentadecane. Both syntheses are described.

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