New synthetic route to the alkaloid withasomnine by ring transformation of a functionalized cyclopropanol via the parent pyrrolo[1,2-b]pyrazole

Add time:08/18/2019    Source:sciencedirect.com

Withasomnine has been prepared by rearrangement of 1-(3-chloropropyl)-cyclopropanol into 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole, followed by bromination and [NiCl2(dppp)]-catalyzed phenylation.

We also recommend Trading Suppliers and Manufacturers of 5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole (cas 107862-65-7). Pls Click Website Link as below: cas 107862-65-7 suppliers

Prev:Research paperALK5 kinase inhibitory activity and synthesis of 2,3,4-substituted 5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles
Next:Bifunctional 3-hydroxy-4-pyridinones as effective aluminium chelators: synthesis, solution equilibrium studies and in vivo evaluation)