(1S,2S)-1-Amino-2-hydroxy-1,2,3,4-tetrahydronaphthalene: a new chiral auxiliary for asymmetric Reformatsky reactions

Add time:08/17/2019    Source:sciencedirect.com

(1S,2S)-1-Amino-2-hydroxy-1,2,3,4-tetrahydronaphthalene, synthesized via a chemoenzymatic approach from naphthalene, has been successfully used as a chiral auxiliary in Reformatsky-type reactions between the corresponding α-bromoacyloxazolidinone and carbonyl compounds.

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