Cyclization of 5-(2-chloroethoxy)-1,5-dihydro-2H-pyrrol-2-ones
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Add time:08/19/2019 Source:sciencedirect.com
The intramolecular cyclization of substituted 5-(2-chloroethoxy)-1,5-dihydro-2H-pyrrol-2-ones in the presence of lithium diisopropylamide hexamethylphosphoramide in tetrahydrofuran gave tetrahydropyrano[2,3-b]pyrrol-6(2H)-ones and 3,4-dihydro-2H-pyrrolo-[2,1-b][1,3]oxazin-6(8aH)-ones in moderate to good yields.
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