Basic NeuroscienceIncreased anesthesia time using 2,2,2-tribromoethanol (cas 1329-86-8)–chloral hydrate with low impact on mouse psychoacoustics

Add time:08/18/2019    Source:sciencedirect.com

BackgroundTo examine psychoacoustics in mice, we have used 2,2,2-tribromoethanol anesthesia in multiple studies. We find this drug is fast-acting and yields consistent results, providing 25–30 min of anesthesia. Our recent studies in binaural hearing prompted development of a regimen to anesthesia time to 1 h. We tested a novel cocktail using 2,2,2-tribromoethanol coupled with low dose chloral hydrate to extend the effective anesthesia time.

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