Original articleSynthesis of some thiopyrimidine and thiazolopyrimidines starting from 2,6-dibenzylidene-3-METHYLCYCLOHEXANONE (cas 1331-22-2) and its antimicrobial activities
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Add time:08/18/2019 Source:sciencedirect.com
A series of novel N-substituted arylidene, pyrazole, thioxopyrimidine and thiazolopyrimidine derivatives 2–7 were synthesized by initial reactions of 2-methyl-cyclohexanone with aromatic aldehydes to give 2,6-dibenzylidene-3-methylcyclohexanone 2. Some of the synthesized compounds were tested as antimicrobial agents. The detailed synthesis, spectroscopic data, and antimicrobial activities of the synthesized compounds were reported.
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