Preliminary communication/CommunicationAccess to NH-aziridine-2-carboxamides through Davidsen acylimidodicarbonate activation
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Add time:08/18/2019 Source:sciencedirect.com
Acylimidodicarbonates obtained from aziridine-2-carboxamides through Davidsen bis-Boc activation react with amine nucleophiles under mild conditions to form tertiary aziridine-2-carboxylic acid amides. NH aziridine-2-carboxylic acid amides were obtained by hydrogenolythic deprotection of N-Cbz derivatives.
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