Generation of 5,6-dimethylene-2(1H)-pyridinones from [3,4-b] sulfolene pyridinones and application in Diels–Alder reactions

Add time:08/18/2019    Source:sciencedirect.com

2(1H)-Pyrazinones were converted into various [3,4-b] sulfolene pyridinones 19–21, serving as precursors for thermolytic conversion into the corresponding 5,6-dimethylene 2(1H)-pyridinone ortho-quinodimethanes. These were trapped in situ by reaction with various dienophiles. Tethering of precursor 19 with a dienophilic side chain attached to the 7-position of the [3,4-b] sulfolene pyridinone also enabled intramolecular cycloaddition when no rearrangement by 1,5-H-shift was viable.

We also recommend Trading Suppliers and Manufacturers of 6-Chloro-1-methyl-2(1H)pyridinone (cas 17228-63-6). Pls Click Website Link as below: cas 17228-63-6 suppliers

Prev:Structure and vibrational assignment of tautomerism of 4-HYDROXYQUINAZOLINE (cas 17227-47-3) in gaseous and aqueous phases
Next:Synthesis and biological evaluation of pyridinone analogues as novel potent HIV-1 NNRTIs)