Featured ArticleTranslational inhibition of APP by Posiphen (cas 116839-68-0): Efficacy, pharmacodynamics, and pharmacokinetics in the APP/PS1 mouse

Add time:08/18/2019    Source:sciencedirect.com

IntroductionTranslational inhibition of amyloid precursor protein (APP) by Posiphen has been shown to reduce APP and its fragments in cell culture, animal models, and mildly cognitively impaired patients, making it a promising drug candidate for the treatment of Alzheimer's disease.

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