Synthesis and photophysical characterization of 1- and 4-(purinyl)triazoles

Add time:08/23/2019    Source:sciencedirect.com

Fluorescent adenine mimetics are useful tools for studying DNA, RNA and enzyme functions. Herein we describe the synthesis of eight 1-(purinyl)triazoles and two 4-(purinyl)triazoles utilizing the 1,4-regioselective copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction as the key step. The fluorescence properties of five of the synthesized 1-(purinyl)triazoles are also presented. The five measured compounds displayed low quantum yields. The results, when compared to previously published data, suggest a high influence of the substitution pattern of the triazole on the fluorescence properties.

We also recommend Trading Suppliers and Manufacturers of S-(6-purinyl)glutathione (cas 136040-02-3). Pls Click Website Link as below: cas 136040-02-3 suppliers

Prev:Enzymology of Cysteine S-Conjugote β-Lyases
Next:Tritylpyridinium tetrakis(pentafluorophenyl)borate as an efficient activator for “constrained-geometry” catalysts in ethylene polymerization)