α′-Benzoyloxy and α′-methoxymethoxy lithium enolates giving opposite diastereofacial selectivities in aldol reactions. Use of (probable) extended chelation for reversal of stereoselectivities

Add time:08/19/2019    Source:sciencedirect.com

The Li enolates of α-benzoyloxy and α-methoxymethoxy ketones 1a and 1c afford nonchelation and chelation aldol products, respectively, both with usefully high diastereofacial selectivities. Evidence suggests that transition state chelation of the benzoyl C=O is responsible for the observed “nonchelation” stereoselectivity of 1a.

We also recommend Trading Suppliers and Manufacturers of 2-(Methoxymethoxy)-1,3-propanediyl Dibenzoate (cas 110874-21-0). Pls Click Website Link as below: cas 110874-21-0 suppliers

Prev:Effect of swift heavy ion irradiation on ethylene–chlorotrifluoroethylene copolymer
Next:Preparation of five- and six- membered cyclic ketones by the palladium-catalyzed cyclization reaction. Application to methyl dihydrojasmonate synthesis)