Synthesis and immunoadjuvant activity of 2,2′-O-[2,2′-diacetamido-2,3,2′,3′-tetradeoxy-6,6′-di-O-(2-tetradecyl-hexadecanoyl)-α, α′-trahalose-3,3′-diyl]bis(N-d-lactoyl-l-alanyl-d-isoglutamine)☆

Add time:08/20/2019    Source:sciencedirect.com

The disaccharide of 6-O-(2-tetradecylhexadecanoyl)muramoyl dipeptide coupled through an α-(1↔1)-α linkage, named in the title, and an analog bearing a single peptide moiety, have been synthesized from 2,2′-diazido-2,2′-dideoxy-α,α′-trehalose. The immunoadjuvant activities of the products were examined.

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