α-Methoxymethyl ketones via aldol reaction
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Add time:08/20/2019 Source:sciencedirect.com
Paraformaldehyde in a methanolic solution of KOH converts ketones into α-methoxymethylated and α- hydroxymethylated products. The method was tested on nine steroidal ketones. On prolonged treatment the ketones formed are reduced to alcohols.
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