Synthesis of new five-membered N-heterocycle derivatives of mono- and bis-phosphonic acids

Add time:07/13/2019    Source:sciencedirect.com

The new functionalized hydroxymethylphosphonic and methylenebis(phosphonic) acids are synthesized via reaction of tris(trimethylsilyl) phosphite and N-formyl derivatives of five-membered N-heterocycles in the presence of trimethylsilyl triflate.

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