4-Chloro-3-(trifluoroacetyl)coumarin as a novel building block for the synthesis of 7-(trifluoromethyl)-6H-chromeno[4,3-b]quinolin-6-ones
-
Add time:08/20/2019 Source:sciencedirect.com
4-Chloro-3-(trifluoroacetyl)coumarin was synthesized for the first time via direct TMSCl-mediated acylation of 4-hydroxycoumarin with TFAA followed by the treatment with POCl3. The reaction of 4-chloro-3-(trifluoroacetyl)coumarin with commercially available anilines is a two-step method, which affords a set of 7-(trifluoromethyl)-6H-chromeno[4,3-b]quinolin-6-ones in good to excellent yields.
We also recommend Trading Suppliers and Manufacturers of 6-CHLORO-4-HYDROXYCOUMARIN (cas 19484-57-2). Pls Click Website Link as below: cas 19484-57-2 suppliers
Prev:Structural and spectral studies of thiosemicarbazones derived from 3- and 4-formylpyridine and 3- and 4-acetylpyridine
Next:Hydroxycoumarins as selective MAO-B inhibitors) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Synthesis, optical and photoelectrical characterizations of the novel 10-chloro-6H,8H-dichromeno[2,3-b:3′,4′-e]pyridine-6,8-dione (CDPD) and its photodiode application08/24/2019
- Synthesis of new5-alkylidene-4-chloro-5H-1,2,3-dithiazoles and their stereochemistry08/23/2019
- Coumarins incorporating hydroxy- and chloro-moieties selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II08/22/2019
- Hydroxycoumarins as selective MAO-B inhibitors08/21/2019
