Interaction of Erucic Acid (cas 112-86-7) with bovine serum albumin using a multi-spectroscopic method and molecular docking technique
-
Add time:08/28/2019 Source:sciencedirect.com
Overconsumption of Erucic Acid (cas 112-86-7) has been shown to cause heart damage in animals. The aim of this study is to evaluate the binding behaviour between erucic acid and bovine serum albumin using multi-spectroscopic methods and a molecular docking technique under physiological conditions. We find that erucic acid can quench the intrinsic fluorescence of BSA by dynamic quenching and there is a single class of binding site on BSA. In addition, the thermodynamic functions ΔH and ΔS are 119.14 kJ mol−1 and 488.89 J mol−1 K−1, indicating that the hydrophobic force is a main acting force. Furthermore, the protein secondary structure changes with an increase in the content of α-helix, measured using synchronous fluorescence, circular dichroism and Fourier transform infrared spectroscopies. The molecular docking results illustrate that erucic acid can bind with the subdomain IIA of the BSA, and hydrogen bonding is also an acting force.
We also recommend Trading Suppliers and Manufacturers of Erucic Acid (cas 112-86-7). Pls Click Website Link as below: cas 112-86-7 suppliers
Prev:Erucic Acid (cas 112-86-7), a component of Lorenzo's oil and PPAR-δ ligand modifies C6 glioma growth and toxicity of doxorubicin. Experimental data and a comprehensive literature analysis
Next:(Micro)structure, thermal behavior and mechanical properties of ethylene–propylene–1-OCTADECENE (cas 112-88-9) terpolymers from chain-walking polymerization of 1-OCTADECENE (cas 112-88-9)) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Erucic Acid (cas 112-86-7), a component of Lorenzo's oil and PPAR-δ ligand modifies C6 glioma growth and toxicity of doxorubicin. Experimental data and a comprehensive literature analysis08/27/2019
- Binding of Erucic Acid (cas 112-86-7) with human serum albumin using a spectroscopic and molecular docking study08/26/2019
- Enrichment of Erucic Acid (cas 112-86-7) from pennycress (Thlaspi arvense L.) seed oil08/25/2019
- The memory-enhancing effect of Erucic Acid (cas 112-86-7) on scopolamine-induced cognitive impairment in mice08/24/2019
- Various concentrations of Erucic Acid (cas 112-86-7) in mustard oil and mustard08/23/2019
- Effect of Erucic Acid (cas 112-86-7) on the rheological and surface properties of coal tar pitch08/22/2019
- ReviewPPAR-δ and Erucic Acid (cas 112-86-7) in multiple sclerosis and Alzheimer's Disease. Likely benefits in terms of immunity and metabolism08/21/2019
- Short communicationUse of Raman spectroscopy for determining Erucic Acid (cas 112-86-7) content in canola oil08/20/2019
-
Health and Chemical more >