Case reportNew onset acute pulmonary edema after METHYLERGONOVINE (cas 113-42-8) given during cesarean delivery of a patient with undiagnosed Raynaud’s disease

Add time:08/21/2019    Source:sciencedirect.com

Raynaud’s disease is a medical condition in which arterial spasm causes episodes of reduced blood flow, in the setting of certain triggers such as cold weather. Patients with this condition are at risk of adverse reactions if they receive medications with vasoactive properties. METHYLERGONOVINE (cas 113-42-8) maleate is one drug used during cesarean delivery to treat postpartum hemorrhage due to uterine atony. By acting directly on uterine and vascular smooth muscle, it produces cardiovascular responses such as coronary vasospasm, myocardial infarction, and even cardiac arrest. However, pulmonary events have rarely been reported. We report our anesthetic management of a 36-year-old patient, with undiagnosed Raynaud’s disease and undergoing cesarean delivery, who experienced new onset acute pulmonary edema after methylergonovine administration to manage postpartum hemorrhage.

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