Original articleMorpholine triflate promoted one-pot, four-component synthesis of dihydropyrano[2,3-c]pyrazoles
-
Add time:08/26/2019 Source:sciencedirect.com
A one-pot, four-component reaction of ethyl acetoacetate, hydrazine hydrate, aldehydes, and malononitrile was discussed using Lewis acid catalyst morpholine triflate (MorT) to afford a series of dihydropyrano[2,3-c]pyrazoles, which were generally catalyzed by organic alkalis. Moderate to excellent yields, no chromatographic purification, and evasion of environmentally hazardous solvents in the reaction process make this protocol very useful for academia and industry.
We also recommend Trading Suppliers and Manufacturers of 4-(3-Nitrophenyl)morpholine (cas 116922-22-6). Pls Click Website Link as below: cas 116922-22-6 suppliers
Prev:Antihyperlipidemic morpholine derivatives with antioxidant activity: An investigation of the aromatic substitution
Next:Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes08/27/2019
- Antihyperlipidemic morpholine derivatives with antioxidant activity: An investigation of the aromatic substitution08/25/2019
- Lewis acid mediated intramolecular C–O bond formation of alkanol-epoxide leading to substituted morpholine and 1,4-oxazepane derivatives: total synthesis of (±)–Viloxazine08/24/2019
- Synthesis of alkyl N-(4-nitrophenyl)-3/2-oxomorpholine-2/3-carboxylates by rhodium(II) acetate catalyzed O–H and N–H carbene insertion08/23/2019
- Laboratory noteSynthesis of Schiff bases of 4-(4-aminophenyl)-morpholine as potential antimicrobial agents08/22/2019
- Research paperSynthesis and biological screening for cytotoxic activity of N-substituted indolines and morpholines08/21/2019
