Novel approach toward the morphine skeleton. Synthesis of 1-(5-benzyloxy-2-bromo-4-methoxybenzyl)-6-oxo-3,4,6,7,8,8a-hexahydro-1H-isoquinoline-2-carboxylic acid phenyl ester via N-acylpyridinium salt chemistry

Add time:08/23/2019    Source:sciencedirect.com

A dihydropyridone-mediated approach to the morphine skeleton was investigated. The hexahydroisoquinoline 2 was synthesized in nine steps using N-acylpyridinium chemistry and dihydropyridone functionalization methods. This new approach should be useful in the design of more efficient syntheses of morphine and its derivatives.

We also recommend Trading Suppliers and Manufacturers of N-(4-BENZYLOXY-PHENYL)-2-CHLORO-ACETAMIDE (cas 19514-92-2). Pls Click Website Link as below: cas 19514-92-2 suppliers

Prev:Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines
Next:Identification of N-Hydroxycinnamamide analogues and their bio-evaluation against breast cancer cell lines)