One-pot synthesis of nucleoside 3′-O-(S-phenyl methanephosphonothioates)

Add time:08/21/2019    Source:sciencedirect.com

The one-pot reaction of nucleosides with MeP(O)Cl2 and thiophenol, providing nucleoside 3′-O-(S-phenyl methanephosphonothioate), potential monomers for the synthesis of oligonucleoside methanephosphonate, is described.

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