N-(3-chloropropyl)phenylethylamine as a possible prodrug of β-phenylethylamine: Studies in the rat brain

Add time:08/22/2019    Source:sciencedirect.com

1.1. N-(3-chloropropyl)phenylethylamine (cas 110970-01-9) (CPPEA) was examined as a possible prodrug of the neuromodulator trace amine β-phenylethylamine (PEA) in rat tissues.2.2. CPPEA produced sustained elevation of PEA levels in rat brain, blood and liver.3.3. Rat brain concentrations of noradrenaline, dopamine and 5-hydroxytryptamine were decreased by administration of CPPEA.

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