Novel synthesis of 1,4-thiazin-2-one O-(tert-butyl) oximes and benzo[b][1,4]thiazin-2-one O-(tert-butyl) oximes in the presence of K2CO3/SiO2
-
Add time:08/24/2019 Source:sciencedirect.com
A simple and efficient method was developed for the synthesis of 1,4-thiazin-2-one O-(tert-butyl) oximes and benzo[b][1,4]thiazin-2-one O-(tert-butyl) oximes from N-tert-butoxy acyl imidoyl bromides and 2-aminothiols in the presence of K2CO3/SiO2. Twenty five novel compounds were readily synthesized in excellent yields using this procedure. The products possessed Z-stereochemistry with regard to the CN double bond. The reaction proceeded with initial substitution of bromine in the N-tert-butoxy acyl imidoyl bromides by mercapto groups in the presence of K2CO3/SiO2, and subsequent intramolecular Schiff base formation.
We also recommend Trading Suppliers and Manufacturers of (R)-4-HYDROXYMETHYL-2,2-DIMETHYL-OXAZOLIDINE-3-CARBOXYLIC ACID TERT-BUTYL ESTER (cas 108149-63-9). Pls Click Website Link as below: cas 108149-63-9 suppliers
Prev:The carboxyl derivatives of 6,8-di-(tert.-butyl)phenoxazine: Synthesis, oxidation reactions and fluorescence
Next:The revisited synthesis of tert-butyl pyroglutamate derivatives) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Alternating radical copolymerization of vinyl acetate and tert-butyl-2-trifluoromethacrylate08/28/2019
- tert-Butyl esters of peptides as organocatalysts for the asymmetric aldol reaction08/27/2019
- Synthesis in aqueous media of poly(ethylene phosphoric acids) by mild thermolysis of homopolymers and block copolymers based on tert-butyl ethylene phosphate08/26/2019
- The revisited synthesis of tert-butyl pyroglutamate derivatives08/25/2019
- The carboxyl derivatives of 6,8-di-(tert.-butyl)phenoxazine: Synthesis, oxidation reactions and fluorescence08/23/2019
- An efficient synthesis of tert-butyl ethers/esters of alcohols/amino acids using methyl tert-butyl ether08/22/2019
