A concise synthesis of 12-(3'-hydroxy-n-propyl)-deoxoartemisinin
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Add time:08/28/2019 Source:sciencedirect.com
The 12-(3'hydroxy-n-propyl)-deoxoartmisinin was synthesized from artemisinic acid via photooxidative cyclization as a key step. The title compound 6a is found to show five times greater in vitro antimalarial acitivity compared to artemisinin.
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