Short reviewRIFM fragrance ingredient safety assessment, 2-Methyl-3-buten-2-ol (cas 115-18-4), CAS Registry Number 115-18-4

Add time:08/26/2019    Source:sciencedirect.com

The use of this material under current use conditions is supported by the existing information.This material was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization potential as well as environmental safety. Repeated dose, developmental, and reproductive toxicities were determined to have the most conservative systemic exposure derived NO[A]EL of 50 mg/kg/day, based on OECD gavage toxicity studies in rats, that resulted in a MOE of 4545455 after considering 100% absorption from skin contact and inhalation. A MOE of >100 is deemed acceptable.

We also recommend Trading Suppliers and Manufacturers of 2-Methyl-3-buten-2-ol (cas 115-18-4). Pls Click Website Link as below: cas 115-18-4 suppliers

Prev:ReviewFragrance material review on 3-methyl-2-buten-1-ol
Next:Experimental and theoretical study of the reaction of 2-Methyl-3-buten-2-ol (cas 115-18-4) with Mu)