Pharmacological inhibition of SUMO-1 with ginkgolic acid alleviates cardiac fibrosis induced by myocardial infarction in mice
-
Add time:08/31/2019 Source:sciencedirect.com
Background and purposeProtein modification by small ubiquitin-like modifier (SUMO) plays a critical role in the pathogenesis of heart diseases. The present study was designed to determine whether ginkgolic acid (GA) as a SUMO-1 inhibitor exerts an inhibitory effect on cardiac fibrosis induced by myocardial infarction (MI).
We also recommend Trading Suppliers and Manufacturers of Ginkgolic Acid C17:1 (cas 111047-30-4). Pls Click Website Link as below: cas 111047-30-4 suppliers
Prev:Research paperCyclosporin A affects the bioavailability of ginkgolic acids via inhibition of P-gp and BCRP
Next:Suzuki–Miyaura reactions of 3,5-dichloro-2,4,6-trifluoropyridine) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Research paperCyclosporin A affects the bioavailability of ginkgolic acids via inhibition of P-gp and BCRP08/30/2019
- Simultaneous quantification and semi-quantification of ginkgolic acids and their metabolites in rat plasma by UHPLC–LTQ–Orbitrap–MS and its application to pharmacokinetics study08/29/2019
- Ginkgolic acids and Ginkgo biloba extract inhibit Escherichia coli O157:H7 and Staphylococcus aureus biofilm formation08/28/2019
- An efficient method for the preparative separation and isolation of ginkgolic acids from the sarcotesta of Ginkgo biloba L by pH-zone-refining counter-current chromatography coupled with inner-recycling mode08/27/2019
- Non-specific SIRT inhibition as a mechanism for the cytotoxicity of ginkgolic acids and urushiols08/26/2019
- 1H NMR-based metabolomics study of liver damage induced by ginkgolic acid (15:1) in mice08/25/2019
- Metabolic profile of ginkgo kernel juice fermented with lactic aicd bacteria: A potential way to degrade ginkgolic acids and enrich terpene lactones and phenolics08/24/2019
- The catalytic activity for ginkgolic acid biodegradation, homology modeling and molecular dynamic simulation of salicylic acid decarboxylase08/23/2019
- Thermal stability of ginkgolic acids from Ginkgo biloba and the effects of ginkgol C17:1 on the apoptosis and migration of SMMC7721 cells08/22/2019
-
Health and Chemical more >