Stereoselective Transformation of 2H-1,4-Oxazin-2-ones into 2,(2),5,5-Tri- and Tetrasubstituted Analogues of cis-5-Hydroxy-2-piperidinemethanol and cis-5-Hydroxy-6-oxo-2-piperidinecarboxylic Acid
-
Add time:08/24/2019 Source:sciencedirect.com
2,(2),5,5-Tri- and tetrasubstituted analogues of 5-hydroxy-2-piperidinemethanol and 5-hydroxy-6-oxo-2-piperidinecarboxylic acid have been prepared via Diels–Alder reaction of 3-substituted 2H-1,4-oxazin-2-ones with ethene followed by functional group transformation of the resulting imidoyl chloride and lactone groups. Some of the 2-piperidinemethanol products are converted further into potential substance P antagonists.
We also recommend Trading Suppliers and Manufacturers of 1-Piperidinecarboxylic acid, 2-hydroxy-, ethyl ester (cas 111054-63-8). Pls Click Website Link as below: cas 111054-63-8 suppliers
Prev:Synthesis of labelled compoundSynthesis of (R)-1-(4-[11C]-p-methoxyphenyl-4-phenyl-3-butenyl)-3-piperidinecarboxylic acid for positron emission tomography of the GABA uptake carrier
Next:Analysis and mass spectrometric characterization of the insect repellent Bayrepel and its main metabolite Bayrepel-acid☆) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Original ArticlesN-[11C]methylpiperidine esters as acetylcholinesterase substrates: an in vivo structure–reactivity study08/27/2019
- Investigation of platelet aggregation inhibitory activity by phenyl amides and esters of piperidinecarboxylic acids08/26/2019
- Analysis and mass spectrometric characterization of the insect repellent Bayrepel and its main metabolite Bayrepel-acid☆08/25/2019
- Synthesis of labelled compoundSynthesis of (R)-1-(4-[11C]-p-methoxyphenyl-4-phenyl-3-butenyl)-3-piperidinecarboxylic acid for positron emission tomography of the GABA uptake carrier08/23/2019
- Gram-scale, chemoselective synthesis of N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-oxopiperidine-3-carboxamide (HIOC)08/22/2019
-
Health and Chemical more >
-
Related Products
- 1-Piperidinecarboxylic acid, 3-(4-nitrophenoxy)-, 1,1-dimethylethyl ester
- 1-Piperidinecarboxylic acid, 4-[[[2-[4-fluoro-3-(trifluoromethyl)phenyl]-2-oxoethyl]amino]carbonyl]-, 1,1-dimethylethyl ester
- 1-Piperidinecarboxylic acid, 4-benzoyl-, 1,1-dimethylethyl ester
- 1-Piperidinecarboxylic acid,4-[[4-(ethoxycarbonyl)-2-methoxyphenoxy]methyl]-, 1,1-dimethylethyles
- 1-Piperidinecarboxylic acid,4-[4-[6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-pyridinyl]-1H-pyrazol-1-yl]-, 1,1-dimethylethyl ester
- Acid Black 1
- Acid Black 107
- Acid Black 168
- Acid Black 194
- Acid Black 2