Excretion of 3-hydroxy-diflunisal as a monosulphate conjugate—identification using ESI-MS

Add time:08/23/2019    Source:sciencedirect.com

Electrospray-ionization mass spectrometry was used to identify a novel, highly polar metabolite of diflunisal isolated from Gunn rat urine. Negative ion spectra were obtained of the sulphate conjugate of diflunisal and the new metabolite, which was identified as a sulphate conjugate of 3-hydroxydiflunisal.

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