Reactions of 7-methoxyimino-4-methylchromene-2,8-dione with phosphines. Preparation of N-substituted 7-amino-8-hydroxy-4-methyl-2H-[1]-benzopyran-2-ones

Add time:08/30/2019    Source:sciencedirect.com

7-Methoxyimino-4-methylchromene-2,8-dione 2 reacts with triarylphosphines 1(a-d) to give the unexpected 7-arylamino-8-hydroxy-4-methyl-2H-[1]-benzopyran-2-ones 7(a-d) and methyl diarylphosphinates 8(a-d) in high yields. The reaction of 2 with trialkylphosphines 1(e,f) as well as with diphenylphosphine 15 leads to the formation of the N-dialkylphosphinoyl derivatives 11, 12, 14 and the N-diphenylphosphinoyl derivative 19, along with compounds 7(e,f). The methylation of compounds 7a, 7f, 11 and 19 is also studied and reaction mechanisms to explain the formation of the products obtained are suggested.

We also recommend Trading Suppliers and Manufacturers of 2-(1-(methoxyimino)ethyl)-5,5-dimethyl-3-hydroxycyclohex-2-en-1-one (cas 108220-95-7). Pls Click Website Link as below: cas 108220-95-7 suppliers

Prev:Synthesis and NK1/NK2 receptor activity of substituted-4(Z)-(methoxyimino)pentyl-1-piperazines
Next:Synthesis of some fused pyridine-and oxazole-polycyclic systems from 10-(methoxyimino)phenanthren-9-one)