α-Methylene β-amino phosphonic ester derivatives by amination of (1-trimethylsilanylmethyl-vinyl) phosphonic esters

Add time:07/13/2019    Source:sciencedirect.com

(1-Trimethylsilanylmethyl-vinyl)-phosphonic esters are synthesised via Wittig–Horner reactions starting from methylenediphosphonic esters. The reactions of (1-trimethylsilanylmethyl-vinyl)-phosphonic esters with NsONHCO2Et and CaO, produce α-methylene N-(ethoxycarbonyl) β-amino phosphonic esters, isolated up to 60% yield, through addition of (ethoxycarbonyl) amine function on the double bond and silyl group elimination.

We also recommend Trading Suppliers and Manufacturers of (1-amino-2-propenyl)phosphonic acid (cas 100432-06-2). Pls Click Website Link as below: cas 100432-06-2 suppliers

Prev:Morpholino Antisense Oligomers as a Potential Therapeutic Option for the Correction of Alternative Splicing in PMD, SPG2, and HEMS
Next:Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice)