A novel catalyst-free, eco-friendly, on water protocol for the synthesis of 2,3-dihydro-1H-perimidines
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Add time:08/24/2019 Source:sciencedirect.com
The first greenest methodology for the synthesis of 2,3-dihydro-1H-perimidines on water is described. 1,8-Diamino naphthalene was reacted with different types of aldehydes at room temperature to furnish the product in moderate to excellent yields in 30 min. A multi-gram scale reaction is also performed to ensure the scalability of the reaction.
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