Furanonaphthoquinones, atraric acid and a benzofuran from the stem barks of Newbouldia laevis

Add time:08/24/2019    Source:sciencedirect.com

The series of naturally occurring furanonaphthoquinones is extended by identification of the derivatives 2-(1′-methylethenyl)-5-hydroxynaphtho[2,3-b]furan-4,9-dione and 2-(1′-methylethenyl)-7-hydroxynaphtho[2,3-b]furan-4,9-dione. They are accompanied in the stem barks of Newbouldia laevis by the known analogues 5-hydroxy-dehydro-iso-α-lapachone, 2-acetyl-5-hydroxynaphtho[2,3-b]furan-4,9-dione and 2-(1′-methylethenyl)naphtho[2,3-b]furan-4,9-dione along with the rare atraric acid and the new 2-(1′-methylethenyl)-6-hydroxy-2,3-dihydrobenzofuran. The structures of these compounds were established from spectroscopic studies.

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