Cu(OAc)2-catalyzed direct radical C2 arylation of quinoline N-oxide with arylamines
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Add time:07/16/2019 Source:sciencedirect.com
A Cu(OAc)2-catalyzed synthesis of 2-arylquinoline N-oxides with easily available arylamines is described. The main features of this reaction are mild reaction conditions, high functional-group tolerance, excellent regioselectivity, and good to excellent yields. This procedure is mild, operationally simple, and constitutes a greener approach to the arylation of quinoline N-oxides.
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