Synthesis of a potential photoaffinity labelling reagent for HIV-1 reverse transcriptase
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Add time:08/29/2019 Source:sciencedirect.com
An analogue (6) of a specific anti-HIV-1 lead, 1-[(2-hydroxyethoxy)-methyl]-6-(phenylthio)thymine (1 : HEPT), has been synthesized with an aim to provide a tool that could be used as a specific photoaffinity labelling reagent for the HIV-1 reverse transcriptase.
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