Synthesis of (R)-(+)-methyl 3-amino-3-(5-hydroxy-2-pyridinyl)propanoate, an analog of l-azatyrosine
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Add time:08/28/2019 Source:sciencedirect.com
A concise asymmetric synthesis of (R)-(+)-methyl 3-amino-3-(5-hydroxy-2-pyridinyl)propanoate 2, a β-amino acid analog of l-azatyrosine 1 starting from the commercially available (−)-Andersen reagent (−)-3 in good overall yield is described.
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